In vivo proton magnetic resonance spectroscopy of liver metabolites in non-alcoholic fatty liver disease in rats: T2 relaxation times in methylene protons
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- 作者：Kyu-Ho Songa ; 1 ; Hyeon-Man Baekb ; c ; 1 ; Do-Wan Leea ; 1 ; Bo-Young Choea ; 1 ; bychoe@catholic.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：MRI ; magnetic resonance imaging ; 1H-MRS ; proton magnetic resonance spectroscopy ; NC ; normal-chow ; HF ; high-fat ; PRESS ; point-resolved spectroscopy ; VOI ; volume of interest ; TR ; repetition time ; TE ; echo time ; NSA ; number of signal averages ; VAPOR ; variable pulse power and optimized relaxation delays ; SE ; spin echo ; SNR ; signal-to-noise ratio ; STEAM ; stimulated echo acquisition mode
- 刊名：Chemistry and Physics of Lipids
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：191
- 期：Complete
- 页码：1-7
- 全文大小：1132 K
文摘
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Relaxation time could be useful for quantitative characterization of liver disease.
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Relaxation reflecting J-coupling effect will improve quantification of metabolite.
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1H-MRS allows sufficient spectral resolution and SNR for lipid resonances.