Green synthesis and bioactivity of vaterite-doped beta-dicalcium silicate bone cement

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• 作者：Fei Wang^a ; Zhezhe Xu^a ; Yin Zhang^a ; ^b ; ^{zhang.512@njut.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Jun Li^a ; Shangjiu Nian^a ; Nianying Zhou^a
• 关键词：β-Ca2SiO4 ; Vaterite ; Green synthesis ; Bioactivity
• 刊名：Ceramics International
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：42
• 期：1
• 页码：1856-1861
• 全文大小：1314 K

文摘

.Vaterite-doped beta-dicalcium silicate bone cement has been successfully synthesized by green synthetic method. The purpose is to reduce the adverse effect caused by the hydration products Ca(OH)₂ in the β-Ca₂SiO₄ bone cement, and improve the bioactivity of the β-Ca₂SiO₄ bone cement. The in vitro bioactivity of vaterite-doped β-Ca₂SiO₄ bone cements was evaluated compared with β-Ca₂SiO₄ bone cement without vaterite by soaking in simulated body fluid (SBF) for the same time (3 days). The formation abilities of hydroxyapatite (HAp) on their surfaces were analyzed by XRD, SEM, EDS and FT-IR. In addition, the setting time of vaterite-doped cement was measured. Experimental results demonstrated that vaterite-doped β-Ca₂SiO₄ bone cements could easily induce the formation of HAp on their surfaces after immersion in SBF. And vaterite-doped β-Ca₂SiO₄ bone cement has much better HAp forming ability and appropriate setting time (12±2 min) than the other one, which can not only eliminate the alkali-silica reaction (ASR) for bone cements but also be expected to be a satisfactory substrate for the bone repairing.