Cell membranes: A subjective perspective

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• 作者：Kai Simons ^{simons@mpi-cbg.de" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Lipids ; Membranes ; Lipid rafts ; Lipid&ndash ; protein interactions ; Electrostatic properties ; Mass spectrometry
• 刊名：Biochimica et Biophysica Acta (BBA)-Biomembranes
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：1858
• 期：10
• 页码：2569-2572
• 全文大小：225 K

文摘

Cell membranes have developed a tremendous complexity of lipids and proteins geared to perform the functions cells require. The lipids have for long remained in the background and are now regaining their role as important building blocks of cells. Their main function is to form the matrix of our cell membranes where they support a variety of functions essential for life. This 2-dimensional fluid matrix has evolved unexpected material properties that involve both lipid–lipid and lipid–protein interactions. This perspective is a short summary of the challenges that this field faces and discusses potential ways and means for coming to grips with the properties of this incredible fluid. This article is part of a Special Issue entitled: Biosimulations edited by Ilpo Vattulainen and Tomasz Róg.