- 作者：Eva Arvela ; Maria Sö ; derströ ; m ; Maria Korhonen ; Karoliina Halmesmä ; ki ; Anders Albä ; ck ; Mauri Lepä ; ntalo ; Maarit Venermo ; Fausto Biancari
- 刊名：Journal of Vascular Surgery
- 出版年：2010
- 出版时间：November 2010
- 年：2010
- 卷：52
- 期：5
- 页码：1218-1225
- 全文大小：866 K
Background
Estimation of the risk of adverse long-term outcome is of paramount importance in the treatment of critical limb ischemia (CLI).Methods
We evaluated the accuracy of two specific risk score systems, the Finnvasc score and the modified Prevent III (mPIII) score, in 1425 CLI patients who underwent unilateral, infrainguinal surgical (47.6 % ) or endovascular (52.4 % ) revascularization. The receiver operating characteristic (ROC) curve analysis was used to estimate the predictive value of these risk scoring methods.
Results
The area under the ROC curve of Finnvasc score for prediction of 30-day amputation was 0.609 (95 % confidence interval [CI] 0.549-0.677) and of mPIII score 0.533 (95 % CI 0.457-0.609). The area under ROC curve of Finnvasc score for prediction of 30-day amputation-free survival was 0.622 (95 % CI 0.573-0.671) and of mPIII score 0.588 (95 % CI 0.533-0.642). The area under the ROC curve of Finnvasc score for prediction of 1-year amputation-free survival was 0.630 (95 % CI 0.597-0.663, P < .0001) and of mPIII score 0.634 (95 % CI 0.600-0.667, P < .0001). Finnvasc score predicted leg salvage (relative risk [RR] 1.431, 95 % CI 1.319-1.551), survival (RR 1.233, 95 % CI 1.116-1.363), and amputation-free survival (RR 1.422, 95 % CI 1.319-1.534). mPIII score also predicted leg salvage (RR 1.190, 95 % CI 1.108-1.277), survival (RR 1.245, 95 % CI 1.193-1.300), and amputation-free survival (RR 1.223, 95 % CI 1.176-1.272).
Conclusions
Finnvasc and modified PIII risk scoring methods predict long-term outcome of patients undergoing infrainguinal revascularization for CLI. Finnvasc score seems to perform well also in predicting immediate postoperative outcome.