Improvement of tardive dyskinesia following amisulpride treatment

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• 作者：Vaios Peritogiannis ; Sofia Tsouli ; Spiros Zafiris ; Dimitrios Pappas and Venetsanos Mavreas
• 关键词：Amisulpride ; Clozapine ; Tardive dyskinesia
• 刊名：Progress in Neuro-Psychopharmacology and Biological Psychiatry
• 出版年：2006
• 出版时间：June 2006
• 年：2006
• 卷：30
• 期：4
• 页码：748-750
• 全文大小：84 K

文摘

Tardive dyskinesia (TD) is a persistent, disturbing side effect of antipsychotic drug treatment. It is established that clozapine and other second generation agents cause less TD and may also improve pre-existing TD. We report a case of significant improvement of TD after the administration of amisulpride, a potential D₂/D₃ antagonist that has atypical properties. The possible effect of fast dissociation of D₂ receptors is being discussed.