A concise stereoselective total synthesis of decarestrictine J
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- 作者：RamaKrishnam Raju Addadaa ; b ; Venkata Reddy Regallab ; Mallikarjuna Rao Vajjab ; Venkata Naresh Vemab ; Venkateswara Rao Annaa ; avrchemistry@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Decarestrictine J ; Regioselective ring opening ; tert-Butyldimethylsilyl glycidyl ether ; Yamaguchi esterification ; Ring-closing metathesis
- 刊名：Tetrahedron Letters
- 出版年：2016
- 出版时间：31 August 2016
- 年：2016
- 卷：57
- 期：35
- 页码：3933-3935
- 全文大小：487 K
文摘
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Decarestrictine J was isolated from a culture broth of
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It was shown to inhibit the biosynthesis of cholesterol.
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An alternate and efficient route to total synthesis of decarestrictine J.
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Yamaguchi esterification and ring-closing metathesis (RCM) used as key transformations.