Reversal of Visual Impairment Associated with Vasospasm After Resection of Sphenoclinoidocavernous Meningioma with Intra-Arterial Verapamil

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• 作者：Krishna Amuluru¹ ; ² ; Fawaz Al-Mufti¹ ; ² ; Inder Paul Singh¹ ; ² ; Larry P. Frohman² ; ³ ; Chirag D. Gandhi¹ ; ² ; ⁴ ; James K. Liu¹ ; ⁵ ; ^{james.liu.md@rutgers.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Endovascular treatment ; Ophthalmic artery ; Skull base meningioma ; Sphenoid wing ; Vasospasm ; Vision loss
• 刊名：World Neurosurgery
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：92
• 期：Complete
• 页码：581.e1-581.e5
• 全文大小：1073 K

文摘

Visual loss can be encountered in the immediate, early, or even delayed postoperative period after resection of skull base meningiomas involving the optic apparatus. Various mechanisms for visual loss can include mechanical injury, vascular insult, optic nerve and chiasm edema, and vasospasm of the blood supply to the visual apparatus.

Case Description

In this article, we describe a patient who developed unilateral visual worsening in the early postoperative period after skull base resection of a sphenoclinoidocavernous meningioma that was compressing the ipsilateral optic nerve. After implementing hyperdynamic therapy and high-dose corticosteroids, catheter angiography showed severe vasospasm of the ipsilateral ophthalmic artery with delayed filling of the choroidal blush. Intra-arterial chemical angioplasty with verapamil was administered that resulted in angiographic improvement and clinical restoration of vision back to preoperative baseline. Vision remained stable in the postoperative course and continued to improve after discharge from the hospital.

Conclusions

To our knowledge, this is the first report of successful reversal of postoperative unilateral visual loss related to vasospasm after resection of a skull base sphenoclinoidocavernous meningioma. This may be a useful strategy to diagnose and treat possible vasospasm-induced visual loss after resection of skull base meningiomas involving the optic apparatus.