Disseminated tumor cells and dormancy in prostate cancer metastasis
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- 作者：Emma E van der Toom
- 刊名：Current Opinion in Biotechnology
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：40
- 期：Complete
- 页码：9-15
- 全文大小：483 K
文摘
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- <p id="par0005">Disseminated tumor cells can be found in the majority of prostate cancer patients, even without clinical evidence of metastatic disease.p>
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- <p id="par0010">The identity and characteristics of circulating and disseminated tumor cells remain unclear.p>
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- <p id="par0015">Autocrine and paracrine signals are likely needed to induce a proliferative switch in dormant prostate cancer DTCs.p>
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- <p id="par0020">Therapies to ‘treat’ DTCs need to be developed.p>