Absence of Pear1 does not affect murine platelet function in vivo
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- 作者：Maarten Criel ; Benedetta Izzi ; Christophe Vandenbriele ; Laurens Liesenborghs ; Soetkin Van kerckhoven ; Marleen Lox ; Katrien Cludts ; Elizabeth A.V. Jones ; Thomas Vanassche ; Peter Verhamme ; Marc Hoylaerts
- 关键词：Platelets ; Pear1&minus ; /&minus ; mice ; Pear1 signaling ; Thrombosis
- 刊名：Thrombosis Research
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：146
- 期：Complete
- 页码：76-83
- 全文大小：1061 K
文摘
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- <p id="p0005">Murine Pear1 is primarily expressed on the platelet membrane.p>
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- <p id="p0010">Platelet Pear1 is phosphorylated during murine platelet aggregation.p>
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- <p id="p0015">Clustering of murine Pear1 triggers platelet aggregation.p>
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- <p id="p0020">Pear1 does not contribute to murine haemostasis or thrombosis.p>