Cervical and ocular vestibular-evoked myogenic potentials in acute vestibular neuritis

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• 作者：Byoung-Soo Shin^a ; ^b ; Sun-Young Oh^a ; ^b ; ^{ohsun@jbnu.ac.kr} ; Ji Soo Kim^c ; Tae-Woo Kim^a ; Man-Wook Seo^a ; ^b ; Hyung Lee^d ; Young-Ae Park^b
• 关键词：Vestibular neuritis ; Cervical vestibular-evoked myogenic potentials (cVEMPs) ; Ocular vestibular-evoked myogenic potentials (oVEMPs) ; Vestibulocollic reflex ; Vestibullo-ocular reflex ; Air-conducted sound
• 刊名：Clinical Neurophysiology
• 出版年：2012
• 出版时间：February 2012
• 年：2012
• 卷：123
• 期：2
• 页码：369-375
• 全文大小：429 K

文摘

Objectives

To clarify the origin and afferent pathways of short-latency ocular vestibular-evoked myogenic potential (oVEMP) in response to air-conducted sound (ACS), we evaluated cervical (cVEMP) and ocular VEMPs in patients with vestibular neuritis (VN).

Methods

In response to air-conducted tone burst, the oVEMP and cVEMP were measured in 60 healthy controls and in 41 patients with acute VN. The VN selectively involved the superior vestibular nerve (superior VN) in 30 patients, affected the inferior vestibular nerve only (inferior VN) in three and damaged both superior and inferior vestibular nerve branches in eight.

Results

All 30 patients with superior VN presented normal cVEMPs, indicating preservation of the saccular receptors and their afferents in the inferior vestibular nerve. However, the oVEMP was abnormal in all patients with superior VN. By contrast, the patients with inferior VN showed normal oVEMP and abnormal cVEMP.

Conclusion

These dissociations in the abnormalities of cVEMP and oVEMP in patients with VN selectively involving the superior or inferior vestibular nerve suggest that the origin of the vestibular nerve afferents of oVEMP differ from those of cVEMP.

Significance

The oVEMP in response to ACS may be mediated by the superior vestibular nerve, probably due to an activation of the utricular receptors.