Arsenite in drinking water produces glucose intolerance in pregnant rats and their female offspring

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• 作者：Mar&iacute ; a Marta Bonaventura^a ; ^b ; ^{mmbonaventura@gmail.com} ; Nadia Soledad Bourguignon^a ; ^{nsbourguignon@yahoo.com.ar} ; Marianne Bizzozzero^a ; ^{m.bizzozzero@hotmail.com} ; Diego Rodriguez^a ; ^{keruvino@hotmail.com} ; Clara Ventura^c ; Claudia Cocca^c ; ^{cmcocca@ffyb.uba.ar} ; Carlos Libertun^a ; ^d ; ^{libertun@dna.uba.ar} ; Victoria Adela Lux-Lantos^a ; ^{vlux@ibyme.conicet.gov.ar} ; ^{vlux@dna.uba.ar} ; ^{vlux@lantos.com.ar}
• 关键词：Arsenite ; Pregnant and postpartum rats ; Offspring ; Body weight ; Glucose intolerance
• 刊名：Food and Chemical Toxicology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：100
• 期：Complete
• 页码：207-216
• 全文大小：1220 K
• 卷排序：100

文摘

Arsenite alters body weight in rats during pregnancy and postpartum. Arsenite alters body weight in offspring from birth until 8 weeks age. Arsenite produces glucose intolerance/impaired insulin secretion in pregnant rats. Arsenite induces glucose intolerance in female offspring. Arsenite induces oxidative stress in liver of female offspring.