K48 linked polyubiquitination is essential for Vif-induced A3G degradation
A3G lysine residues 297, 301, 303, and 334 were not sufficient to render A3G sensitive to Vif- mediated degradation.
Ubiquitin-modified A3G lysine residues contribute differently to HIV-1 Vif-induced A3G degradation.
Ubiquitin modification occurs on lysine residues interspersed throughout A3G.