Oleic acid, hydroxytyrosol and n-3 fatty acids collectively modulate colitis through reduction of oxidative stress and IL-8 synthesis; in vitro and in vivo studies
详细信息 查看全文
- 作者：K. Vijay Kumar Reddy ; K. Akhilender Naidu ; aknaidu@cftri.res.in" class="auth_mail" title="E-mail the corresponding author
- 关键词：Ulcerative colitis ; Medium chain triglycerides ; Hydroxytyrosol ; Fish oil ; Mucosal healing ; Eicosapentaenoic acid ; Docosahexaenoic acid ; Inflammatory cytokines
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：35
- 期：Complete
- 页码：29-42
- 全文大小：2376 K
文摘
- bel">•
Medium chain triglycerides aggravate intestinal inflammation as well as induced cell damage in the Caco-2 cells.
- bel">•
Oleic acid, OH-tyrosol and n-3 fatty acids inhibit colon inflammation and also induced cell damage in the Caco-2 cells.
- bel">•
Feeding fish oil (1.0 or 2.0%) along with MUFA accelerates the mucosal healing process after a short episode of colitis.