Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways
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- 作者：Jian Tan1 ; Craig McKenzie1 ; Peter J. Vuillermin2 ; Gera Goverse3 ; Carola G. Vinuesa4 ; Reina E. Mebius3 ; Laurence Macia1 ; 5 ; 6 ; 7 ; laurence.macia@sydney.edu.au" class="auth_mail" title="E-mail the corresponding author ; Charles R. Mackay1 ; 5 ; 6 ; 7 ; charles.mackay@monash.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：21 June 2016
- 年：2016
- 卷：15
- 期：12
- 页码：2809-2824
- 全文大小：3339 K
文摘
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Dietary fiber with vitamin A increases the potency of tolerogenic CD103+ DCs
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High-fiber diet protects mice against peanut allergy via gut microbiota and SCFA
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High-fiber effects rely on epithelial GPR43 and immune cell GPR109a
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Dietary fiber promotes TFH and IgA responses