Glycine-rich conotoxins from the Virgiconus clade
详细信息 查看全文
- 作者：Samuel S. Espino<sup>asup> ; Taleen Dilanyan<sup>asup><sup> ; sup><sup>bsup> ; Julita S. Imperial<sup>asup><sup> ; sup><sup>imperial@biology.utah.edu" class="auth_mail" title="E-mail the corresponding authorsup><sup> ; sup><sup>jimperial98@gmail.com" class="auth_mail" title="E-mail the corresponding authorsup> ; Manuel B. Aguilar<sup>csup> ; Russell W. Teichert<sup>asup> ; Pradip Bandyopadhyay<sup>asup> ; Baldomero M. Olivera<sup>asup>
- 关键词：Conotoxins ; O1 superfamily ; Virgiconus
- 刊名：Toxicon
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：113
- 期：Complete
- 页码：11-17
- 全文大小：1250 K
文摘
- ss="listitem" id="list_ulist0010">
- ss="label">•
A conotoxin, vi6a, was purified from the venom of C. virgo.
- ss="label">•
vi6a exhibited inhibitory activity in the calcium imaging of dissociated mouse lumbar DRG neurons.
- ss="label">•
Intracranial and intraperitoneal injection of vi6a resulted in hyperactivity in mice.
- ss="label">•
Related conotoxins were identified from other members of the Virgiconus clade.