Transcriptome differences in the rumen of beef steers with variation in feed intake and gain
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- 作者：Rebecca J. Kernb ; Rebecca.Kern@ARS.USDA.GOV" class="auth_mail" title="E-mail the corresponding author ; Amanda K. Lindholm-Perryb ; Amanda.Lindholm@ARS.USDA.GOV" class="auth_mail" title="E-mail the corresponding author ; Harvey C. Freetlyb ; Harvey.Freetly@ARS.USDA.GOV" class="auth_mail" title="E-mail the corresponding author ; Warren M. Snellingb ; Warren.Snelling@ARS.USDA.GOV" class="auth_mail" title="E-mail the corresponding author ; John W. Kernc ; jkern@kernstat.com" class="auth_mail" title="E-mail the corresponding author ; John W. Keelea ; john.keele@ars.usda.gov" class="auth_mail" title="E-mail the corresponding author ; Jeremy R. Milesb ; Jeremy.Miles@ARS.USDA.GOV" class="auth_mail" title="E-mail the corresponding author ; Andrew P. Footeb ; Andrew.Foote@ars.usda.gov" class="auth_mail" title="E-mail the corresponding author ; William T. Oliverb ; William.Oliver@ars.usda.gov" class="auth_mail" title="E-mail the corresponding author ; Larry A. Kuehnb ; Larry.Kuehn@ars.usda.gov" class="auth_mail" title="E-mail the corresponding author ; Paul A. Luddena ; Ludden@uwyo.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：ADFI ; average daily feed intake ; ADG ; average daily gain ; BW ; body weight ; CP ; threshold cycle ; DAVID ; database for annotation ; visualization and integrated discovery ; DEG ; differentially expressed gene(s) ; DMI ; dry matter intake ; FC ; fold change ; FCR ; feed conversion ratio ; FDR ; false discovery rate ; IPA ; Ingenuity Pathway Analysis ; KEGG ; Kyoto Encyclopedia of Genes and Genomes ; PCR ; polymerase chain reaction ; qPCR ; quantitative PCR ; qRT-PCR ; quantitative real time polymerase chain reaction ; RF
- 刊名：Gene
- 出版年：2016
- 出版时间：15 July 2016
- 年：2016
- 卷：586
- 期：1
- 页码：12-26
- 全文大小：466 K
文摘
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This is the first global view of the genes expressed in rumen epithelium as it relates to feed intake and body weight gain.
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High gain-low intake animals produced differentially expressed genes with functions in immune response
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Oxidative stress pathways were identified in comparisons between the high gain-low intake animals and other groups.
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Genes identified in other cattle transcriptome studies were also differentially expressed in this study.
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New genes associated with feed intake and gain were identified in this study and previously identified genes were confirmed.