Association of biometric factors with anterior chamber angle widening and intraocular pressure reduction after uneventful phacoemulsification for cataract

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• 作者：Guofu Huang MD ; PhD ; Eduardo Gonzalez MD ; Roland Lee BA ; Yi-Chun Chen MD ; Mingguang He MD ; PhD ; Shan C. Lin MD  ; ;   ; ^{lins@vision.ucsf.edu}[Author vitae]
• 刊名：Journal of Cataract and Refractive Surgery
• 出版年：2012
• 出版时间：January 2012
• 年：2012
• 卷：38
• 期：1
• 页码：108-116
• 全文大小：430 K

文摘

Purpose

To evaluate anterior chamber biometric factors associated with the degree of angle widening and intraocular pressure (IOP) reduction after phacoemulsification.

Setting

University of California, San Francisco, California, USA.

Design

Case series.

Methods

Anterior chamber parameters obtained by anterior segment coherence tomography were compared preoperatively and 3 months postoperatively. Measurements included the angle opening distance 500 ¦Ìm anterior to the scleral spur (AOD500), trabecular¨Ciris space area 500?¦Ìm from the scleral spur (TISA500), iris curvature (I-Curv), anterior chamber angle (ACA), trabecular¨Ciris space area, anterior chamber volume, anterior chamber width, and lens vault (LV).

Results

The study enrolled 73 eyes. The mean patient age was 77.45 years ¡À 7.84 (SD); 65.75 % of patients were women. From preoperatively to 3 months postoperatively, the mean AOD500 increased significantly (0.254 ¡À 0.105 to 0.433 ¡À 0.108 mm) and the mean IOP decreased significantly (14.97 ¡À 3.35 to 12.62 ¡À 3.37 mm Hg) (P<.001). The reduction in IOP was correlated with the increase in AOD500 (r = 0.240, P=.041) and preoperative LV (r = 0.235, P=.045). After adjusting for related factors, AOD500 widening was positively correlated with LV (¦Â = 0.458, P=.044) and I-Curv (¦Â = 0.235, P=.043) and negatively correlated with preoperative TISA500 (¦Â = ?.269, P=.025) and ACA (¦Â = ?.919, P=.027).

Conclusions

Surgically induced AOD widening was significantly correlated with anterior chamber biometric factors. Preoperative LV appears to be a significant factor in angle widening and IOP reduction after phacoemulsification.

Financial Disclosure

No author has a financial or proprietary interest in any material or method mentioned.