A novel pyrazoline-based fluorescent probe for detection of hydrazine in aqueous solution and gas state and its imaging in living cells
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- 作者：Lei Wanga ; c ; 1 ; scuwill@foxmail.com" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae ; Fei-yan Liub ; c ; 1Author Vitae ; Hai-yang LiucAuthor Vitae ; Yun-sheng DongcAuthor Vitae ; Tian-qi LiucAuthor Vitae ; Ji-feng LiubAuthor Vitae ; You-wei YaocAuthor Vitae ; Xue-juan WandAuthor Vitae
- 关键词：Pyrazoline ; Hydrazine ; Gas detection ; Biological imaging
- 刊名：Sensors & Actuators: B. Chemical
- 出版年：2016
- 出版时间：28 June 2016
- 年：2016
- 卷：229
- 期：Complete
- 页码：441-452
- 全文大小：3547 K
文摘
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A novel fluorescent probe 4 for hydrazine based on pyrazoline-derived was synthesized and characterized.
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The detection limit of probe 4 toward hydrazine is 1.99 ppb at physiological pH.
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The probe 4 could detect hydrazine in gas state with a concentration down to 1.0%.
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The practical application to bioimaging was successfully realized.
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The sensing mechanism is the deprotection of phthalimide which is verified by the absorption spectra, the 1H NMR analysis and HRMS.