Brain heterogeneity leads to differential innate immune responses and modulates pathogenesis of viral infections
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- 作者：Loreen Zegenhagena ; bAuthor Vitae ; Chaitanya KurhadecAuthor Vitae ; Nikolaus KoniszewskibAuthor Vitae ; Anna K. Ö ; verbycAuthor Vitae ; Andrea Krö ; gera ; b ; andrea.kroeger@med.ovgu.de" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：Type I interferon ; Central nervous system ; Brain heterogeneity ; Innate immunity
- 刊名：Cytokine & Growth Factor Reviews
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：30
- 期：Complete
- 页码：95-101
- 全文大小：861 K
文摘
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Brain heterogeneity influences antiviral host responses.
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Innate antiviral response is brain region specific.
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Viral replication and distribution is dependent on various mechanisms.
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Cell type and sub-population display different innate immunity.