Microfluidics for cell-based high throughput screening platforms—A review
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- 作者：Guansheng Dua ; b ; 1Author Vitae ; Qun Fanga ; fangqun@zju.edu.cn" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae ; Jaap M.J. den Toonderb ; j.m.j.d.toonder@tue.nl" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：High throughput screening ; Cell-based microfluidics ; Drug discovery
- 刊名：Analytica Chimica Acta
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：903
- 期：Complete
- 页码：36-50
- 全文大小：5390 K
文摘
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High throughput screening is a major instrument in drug discovery.
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This paper reviews the application of microfluidics to cell-based high throughput screening platforms.
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We describe different modes in microfluidic platforms for cell-based high throughput screening.
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We discuss the advantages and disadvantages of each screening mode.
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We also give a perspective of the future of microfluidics for cell-based high throughput screening platforms.