Intermolecular interactions between B. mori silk fibroin and poly(l-lactic acid) in electrospun composite nanofibrous scaffolds
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- 作者：Paola Taddeia ; paola.taddei@unibo.it" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae ; Silvia Tozzia ; Giampaolo Zuccherib ; cAuthor Vitae ; Simona MartinottidAuthor Vitae ; Elia RanzatodAuthor Vitae ; Valeria ChionoeAuthor Vitae ; Irene CarmagnolaeAuthor Vitae ; Masuhiro TsukadafAuthor Vitae
- 关键词：Electrospinning ; Vibrational spectroscopy ; AFM ; SEM ; Keratinocytes cell cultures
- 刊名：Materials Science & Engineering C
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：70
- 期：part_P1
- 页码：777-787
- 全文大小：1539 K
文摘
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Composite silk fibroin-poly(l-lactic acid) scaffolds were obtained by electrospinning.
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Intermolecular interactions between SF and PLLA were revealed for the first time.
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Upon blending, the crystallisation of PLLA was hindered by the presence of SF.
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SF crystallized preferentially and maintained its prevailing β-sheet structure.
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The incorporation of SF into PLLA enhanced human keratinocytes adhesion and proliferation.