Binary mixtures of neonicotinoids show different transcriptional changes than single neonicotinoids in honeybees (Apis mellifera)

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• 作者：Verena Christen^a ; Sara Bachofer^a ; ^b ; Karl Fent^a ; ^c ; ^{karl.fent@bluewin.ch}
• 关键词：Honeybees ; Neonicotinoids ; Mixture activity ; Transcription analysis ; Nicotinic acetylcholine receptors ; Vitellogenin
• 刊名：Environmental Pollution
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：220
• 期：part_PB
• 页码：1264-1270
• 全文大小：876 K
• 卷排序：220

文摘

Honeybees are exposed to mixtures of neonicotinoids. Neonicotinoids alter transcripts of target genes like vitellogenin. Binary mixtures of neonicotinoids result in lower effects than single neonicotinoids. Binary mixtures of neonicotinoids do not follow the concentration addition model.