KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation
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- 作者：Jun-ichirou Ohzeki1 ; Nobuaki Shono1 ; Koichiro Otake1 ; Nuno M.C. Martins2 ; Kazuto Kugou1 ; Hiroshi Kimura3 ; Takahiro Nagase4 ; Vladimir Larionov5 ; William C. Earnshaw2 ; Hiroshi Masumoto1 ; masumoto@kazusa.or.jp" class="auth_mail" title="E-mail the corresponding author
- 刊名：Developmental Cell
- 出版年：2016
- 出版时间：6 June 2016
- 年：2016
- 卷：37
- 期：5
- 页码：413-427
- 全文大小：6186 K
文摘
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The histone acetyltransferase KAT7 positively regulates centromeric CENP-A assembly
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Human Mis18 complex is a scaffold for assembly of KAT7 and HJURP, a CENP-A chaperone
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KAT7 or RSF1 stimulates histone turnover/exchange on alphoid DNA
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KAT7 antagonizes H3K9-trimethylase Suv39h1-mediated centromere inactivation