Baseline biopsychosocial determinants of telomere length and 6-year attrition rate
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- 作者：Dó ; ra Ré ; vé ; sz ; 1 ; D.Revesz@ggzingeest.nl" class="auth_mail" title="E-mail the corresponding author ; Yuri Milaneschi Y.Milaneschi@ggzingeest.nl" class="auth_mail" title="E-mail the corresponding author ; Erik M. Terpstra E.M.Terpstra@student.vu.nl" class="auth_mail" title="E-mail the corresponding author ; Brenda W.J.H. Penninx B.Penninx@vumc.nl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Telomeres ; Lifestyle ; Metabolic syndrome ; Inflammation ; Autonomic nervous system ; Cortisol
- 刊名：Psychoneuroendocrinology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：67
- 期：Complete
- 页码：153-162
- 全文大小：797 K
文摘
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No large study has systematically explored predictors of telomere length and telomere attrition.
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Sociodemographic, lifestyle, and psychosocial, metabolic and physiological stressors linked with telomere length.
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6-year telomere attrition almost completely predicted by baseline telomere length.
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We suggest a strong internal homeostasis in the telomeric system.
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Identified determinants may be targets of future studies to promote telomere maintenance and healthy aging.