Sleep-wakefulness cycle and behavior in pannexin1 knockout mice

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• 作者：V.M. Kovalzon^a ; L.S. Moiseenko^a ; A.V. Ambaryan^a ; S. Kurtenbach^b ; V.I. Shestopalov^b ; ^c ; Y.V. Panchin^d ; ^e ; ^{ypanchin@yahoo.com}
• 关键词：Pannexin ; Sleep ; Purinergic signaling ; ATP ; Adenosine ; Hemichannels ; Gene knockout models
• 刊名：Behavioural Brain Research
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：318
• 期：Complete
• 页码：24-27
• 全文大小：854 K
• 卷排序：318

文摘

Waking is increased and slow wave sleep is decreased in the dark period in mice deficient for Panx1. Movement activity is increased throughout the light/dark cycle in mice deficient for Panx1. The lack of pannexin modifies animal behavior in vertical and horizontal pole tests.