Myoepithelial carcinoma of the hypopharynx

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• 作者：Kazuhira Endo ; ^{endok@med.kanazawa-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Hiroshi Yoshida ; Yosuke Nakanishi ; Akira Tsuji ; Satoru Kondo ; Naohiro Wakisaka ; Shigeyuki Murono ; Tomokazu Yoshizaki
• 关键词：Myoepithelial carcinoma ; Hypopharynx ; Immunohistochemistry
• 刊名：International Journal of Pediatric Otorhinolaryngology Extra
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：13
• 期：Complete
• 页码：16-18
• 全文大小：929 K

文摘

Primary myoepithelial carcinoma of the hypopharynx is an extremely rare malignant tumor that was first classified as a separate neoplasm by the World Health Organization in 1991. We present an unusual case arising in a 1-year-old boy. He underwent microsuspension direct laryngoscopy with organ preservation. The tumor cells were arranged in nests and lobules separated by thin fibrovascular septae in a background of fibromyxoid stroma. Immunohistochemically, the tumor was positive for S-100 protein, AE1/AE3, and synaptophysin. The tumor was diagnosed as myoepithelial carcinoma. During follow-up for 12 months, there was no clinical or radiological evidence of recurrence or distant metastasis.