Sleep architecture parameters as a putative biomarker of suicidal ideation in treatment-resistant depression

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• 作者：Rebecca A. Bernert^a ; ^{rbernert@stanford.edu} ; David A. Luckenbaugh^b ; Wallace C. Duncan^b ; Naomi G. Iwata^a ; Elizabeth D. Ballard^b ; Carlos A. Zarate^b
• 关键词：Sleep architecture ; Suicide risk ; Depression ; Bipolar disorder ; Treatment-resistance
• 刊名：Journal of Affective Disorders
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：208
• 期：Complete
• 页码：309-315
• 全文大小：295 K
• 卷排序：208

文摘

Suicidal ideation in treatment-resistant depression is linked with less deep sleep. The same group had increased nocturnal wakefulness and decreased sleep efficiency. Effect sizes were greater for those with bipolar than major depressive disorder. Sleep architecture may be a key putative biomarker in suicide prevention.