SVZ choline acetyltransferase (ChAT)+ neurons promote neurogenesis in adult mice.
SVZ neurogenesis was elevated after middle cerebral artery occlusion (MCAO) in mice.
The cholinergic system in the SVZ was activated after MACO.
Post-stroke neurogenesis was enhanced by donepezil and abolished by atropine.
SVZ ChAT+ neurons may promote neurogenesis via the FGFR signaling pathway.