Formulation of porous poly(lactic-co-glycolic acid) microparticles by electrospray deposition method for controlled drug release
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- 作者：Shilei Hao ; Yazhou Wang ; Bochu Wang ; wangbc2000@126.com" class="auth_mail ; Jia Deng ; Liancai Zhu ; Yang Cao
- 关键词：Electrospray deposition ; Porous microparticles ; Entrapment efficiency ; Controlled release ; Cytotoxicity
- 刊名：Materials Science and Engineering: C
- 出版年：1 June 2014
- 年：2014
- 卷：39
- 期：Complete
- 页码：113-119
- 全文大小：1056 K
文摘
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The porous PLGA microparticles were successfully prepared by the electrospray deposition method at one step.
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The porous microparticles had high loading capacity and low density.
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The microparticle showed a sustained release in the simulated gastric liquid.
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The microparticles showed a slight cytotoxicity in vitro.