Surgery for metastatic lesions of the femur: Good outcome after 245 operations in 216 patients

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• 作者：Johan Nilsson ; Pelle Gustafson
• 关键词：Femur ; Skeletal metastasis ; Lesion ; Surgery ; Outcome ; Survival
• 刊名：Injury
• 出版年：2008
• 出版时间：April 2008
• 年：2008
• 卷：39
• 期：4
• 页码：404-410
• 全文大小：105 K

文摘

The decision whether to perform prophylactic surgery on a patient with metastatic carcinoma to bone can be a difficult one, which depends on several complex factors. These factors include the biologic activity of the bone lesion; the responsiveness of the bone lesion to medical and radiation therapy; the anatomic location of the bone metastasis; and patient factors, such as overall health status, expected length of survival, compliance, and patient expectations and needs. These four topics are explored in detail in this article to formulate an appropriate clinical approach to patients with skeletal metastases. With the increased survival of patients with skeletal metastases and the improved nonsurgical treatment for these patients, a careful review is warranted on this subject. This article concludes with a discussion of resection and skeletal reconstruction versus internal fixation of metastatic lesions.