Temperature sensitive auditory neuropathy
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- 作者：Qiujing Zhanga ; zqj99@163.com" class="auth_mail" title="E-mail the corresponding author ; Lan Lana ; ll-301@263.net" class="auth_mail" title="E-mail the corresponding author ; Wei Shia ; sw0215@sohu.com" class="auth_mail" title="E-mail the corresponding author ; Lan Yua ; anna_lan@126.com" class="auth_mail" title="E-mail the corresponding author ; Lin-yi Xiea ; xielinyi1234@126.com" class="auth_mail" title="E-mail the corresponding author ; Fen Xionga ; 870505713@qq.com" class="auth_mail" title="E-mail the corresponding author ; Cui Zhaoa ; zhaocui619@126.com" class="auth_mail" title="E-mail the corresponding author ; Na Lia ; lna301@126.com" class="auth_mail" title="E-mail the corresponding author ; Zifang Yina ; Yinbug@163.com" class="auth_mail" title="E-mail the corresponding author ; Liang Zonga ; cell-099@163.com" class="auth_mail" title="E-mail the corresponding author ; Jing Guana ; ggy3u@126.com" class="auth_mail" title="E-mail the corresponding author ; Dayong Wanga ; wangdy301@126.com" class="auth_mail" title="E-mail the corresponding author ; Wei Sunb ; weisun@buffalo.edu" class="auth_mail" title="E-mail the corresponding author ; Qiuju Wanga ; wqcr@263.net" class="auth_mail" title="E-mail the corresponding author ; wqcr301@sina.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Auditory neuropathy ; Temperature-sensitive ; Cochlear implant ; Otoferlin ; OTOF
- 刊名：Hearing Research
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：335
- 期：Complete
- 页码：53-63
- 全文大小：4689 K
文摘
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We report the clinical and genetic characterization of a very rare hearing loss.
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The hearing of TSAN patients fluctuate with the variation of core body temperature.
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Long term follow up study suggests the hearing loss of TSAN may recover with age.
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Genetic analysis indicates that OTOF mutations underlie the TSAN.