A novel heteropolysaccharide (SGRP1) with notable immunomudulatory activity is obtained from Smilax glabra Roxb.
Structure of SGRP1 is characterized by HPGPC, GC, GC–MS, FT-IR and NMR.
Immunomodulatory effects of SGRP1 are evaluated with RAW264.7 cells.
SGRP1 promote the phagocytosis and increase the secretion of NO, IL-6, TNF-α and IL-1β.
The immunomodularoty mechanism of SGRP1 is elucidated for the first time.