Accelerometry and Its Association With Objective Markers of Walking Limitations in Ambulatory Adults With Multiple Sclerosis

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• 作者：Robert W. Motl ; PhD^a ; ^{robmotl@uiuc.edu" class="auth_mail" title="E-mail the corresponding author} ; Deirdre Dlugonski ; BS^a ; Yoojin Suh ; MS^a ; Madeline Weikert ; BS^a ; Bo Fernhall ; PhD^a ; Myla Goldman ; MD^b
• 关键词：Gait ; Mobility limitation ; Multiple sclerosis ; Rehabilitation ; Walking
• 刊名：Archives of Physical Medicine and Rehabilitation
• 出版年：2010
• 出版时间：December 2010
• 年：2010
• 卷：91
• 期：12
• 页码：1942-1947
• 全文大小：330 K

文摘

Motl RW, Dlugonski D, Suh Y, Weikert M, Fernhall B, Goldman M. Accelerometry and its association with objective markers of walking limitations in ambulatory adults with multiple sclerosis.

Objective

To validate accelerometry based on its correlations with 6-minute walk distance (6MWD) and oxygen cost of walking as objective markers of walking limitations in multiple sclerosis (MS).

Design

Cross-sectional.

Setting

Laboratory and general community.

Participants

Ambulatory participants with MS (N=26) who resided in the local community.

Interventions

Not applicable.

Main Outcome Measures

Patient Determined Disease Steps (PDDS) scale and Multiple Sclerosis Walking Scale-12 (MSWS-12); 6-minute walk test while wearing a portable metabolic unit for measuring the 6MWD and oxygen cost of walking; accelerometer during the waking hours of a 7-day period.

Results

The average of total daily movement counts from the accelerometer correlated significantly and strongly with MSWS-12 scores (ρ=–.681, P=.001), PDDS scores (ρ=–.609, P=.001), 6MWD (ρ=.519, P=.003), and oxygen cost of walking (ρ=–.541, P=.002).

Conclusions

We provide evidence that further supports the validity of accelerometry as a measure of walking limitations in ambulatory persons with MS.