Piceatannol protects ARPE-19 cells against vitamin A dimer-mediated photo-oxidative damage through activation of Nrf2/NQO1 signalling
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- 作者：Bing Lua ; b ; c ; 1 ; Tao Suna ; 1 ; Weinan Lia ; Xiaodong Sunb ; c ; Xiaomin Yaoa ; Xiangjun Suna ; xjsun@sjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Piceatannol ; Oxidative stress ; Nrf2 pathway ; Retinal pigment epithelium (RPE) cells ; Vitamin A dimer
- 刊名：Journal of Functional Foods
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：26
- 期：Complete
- 页码：739-749
- 全文大小：2845 K
文摘
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Piceatannol protects ARPE-19 cells against apoptosis induced by photo-oxidation.
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The protective effect of piceatannol is due to activating the Nrf2/NQO1 pathway.
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PI3K/Akt may be a chief pathway involved in Nrf2/NQO-1 induction by piceatannol.