Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study

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• 作者：Vawter ; Marquis P. ; Crook ; Jeremy M. ; Hyde ; Thomas M. ; Kleinman ; Joel E. ; Weinberger ; Daniel R. ; et. al.
• 关键词：Microarray ; Schizophrenia ; Genomics ; Gene expression ; Postmortem ; Prefrontal cortex
• 刊名：Schizophrenia Research
• 出版年：2002
• 出版时间：November 1, 2002
• 年：2002
• 卷：58
• 期：1
• 页码：11-20
• 全文大小：222 K

文摘

Microarray studies can be used to examine expression levels for large numbers of genes simultaneously and may be applied to identify genes involved in schizophrenia. A microarray with 1127 brain-relevant genes was used to screen relative gene expression in the dorsolateral prefrontal cortex (DLPFC) from three pools of patients with schizophrenia (n