A novel ECL sensor for determination of carcinoembryonic antigen using reduced graphene Oxide-BaYF5:Yb, Er upconversion nanocomposites and gold nanoparticles
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- 作者：Linlin ZhaoaAuthor Vitae ; Juan LiaAuthor Vitae ; Yuhong LiuaAuthor Vitae ; Yuan WeiaAuthor Vitae ; Jin ZhangaAuthor Vitae ; Jinzha ZhangaAuthor Vitae ; Qing XiaaAuthor Vitae ; Qiang ZhangaAuthor Vitae ; Wenbo Zhaoa ; zhaowenbo@njnu.edu.cn" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae ; Xiaoqiang Chenb ; chenxq@njtech.edu.cn" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：Reduced graphene Oxide-BaYF5 ; Yb ; Er nanocomposites ; Surface assembly ; Carcinoembryonic antigen ; Electrochemiluminescence immunosensor
- 刊名：Sensors & Actuators: B. Chemical
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：232
- 期：Complete
- 页码：484-491
- 全文大小：1237 K
文摘
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A ECL sensor was assembled by rGO-BaYF5: Yb, Er prepared in situ hydrothermal.
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ECL intensity of rGO-BaYF5: Yb, Er modified by AuNPs was enhanced 4-fold.
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Immunosensor exhibited high selectivity to CEA with low detection limit.
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The immunosensor was applied to a real sample (human serum samples).
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The immunosensor has advantageous potential for future clinical analysis.