This study determined the acute and potential subchronic toxicities of HBCD in S.D. rats through head/nose-only exposure.
The inhalation LC50(4 h) for HBCD was higher than 5312 ± 278 mg/m3 for both males and females.
In the repeated dose inhalation study, the NOAEL for 14-day repeated dose inhalation toxicity study of HBCD was 2000 mg/m3.