Frequency and Risk Factors Associated with Cord Graft Failure after Transplant with Single-Unit Umbilical Cord Cells Supplemented by Haploidentical Cells with Reduced-Intensity Conditioning
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- 作者：Stephanie B. Tsai1 ; 2 ; s13@bu.edu" class="auth_mail" title="E-mail the corresponding author ; Hongtao Liu1 ; Tsiporah Shore3 ; Yun Fan4 ; Michael Bishop1 ; Melissa M. Cushing5 ; Usama Gergis3 ; Lucy Godley1 ; Justin Kline1 ; Richard A. Larson1 ; Guadalupe Martinez6 ; Sebastian Mayer3 ; Olatoyosi Odenike2 ; Wendy Stock1 ; Amittha Wickrema7 ; Koen van Besien3 ; Andrew S. Artz1
- 关键词：Graft failure ; Alternative donor ; Allogeneic stem cell transplantation ; umbilical cord blood ; Haploidentical graft
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：22
- 期：6
- 页码：1065-1072
- 全文大小：436 K
文摘
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Cord graft failure occurred in 15% of haplo-cord transplantations evaluated in this study.
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Haploidentical or mixed chimerism after cord graft failure provides hematopoiesis after cord graft failure.
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Prolonged survival and disease control is possible in spite of cord graft failure.