A versatile immobilization-free photoelectrochemical biosensor for ultrasensitive detection of cancer biomarker based on enzyme-free cascaded quadratic amplification strategy
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- 作者：Lei Ge ; Wenxiao Wang ; Ting Hou ; Feng Li ; lifeng@qust.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Homogeneous photoelectrochemical assay ; Catalytic hairpin assembly ; Hybridization chain reaction ; DNAzyme ; Catalytic precipitation
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：77
- 期：Complete
- 页码：220-226
- 全文大小：1506 K
文摘
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A versatile immobilization-free PEC biosensor is developed for the very first time.
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This work is the first attempt to integrate the signal amplification of CHA and HCR.
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Ultra-sensitivity is achieved by this enzyme-free cascaded quadratic amplification.