miR-186 inhibits cell proliferation in multiple myeloma by repressing Jagged1
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- 作者：Zengyan Liua ; b ; 1 ; Guoqiang Zhangc ; 1 ; Wenzheng Yub ; Na Gaob ; Jun Penga ; junpeng885@sina.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：miR-186 ; Jagged1 ; Multiple myeloma ; Proliferation
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：469
- 期：3
- 页码：692-697
- 全文大小：1065 K
文摘
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miR-186 expression is decreased in MM.
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miR-186 inhibits MM cell proliferation in vitro and in vivo.
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Jagged1 is regulated by miR-186.
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Overexpression of Jagged1 reverses the effects of miR-186.