Prostate cancer with a pseudocapsule at MR imaging: a marker of high grade and stage disease?

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• 作者：Apurva A. Bonde^a ; Elena K. Korngold^a ; Bryan R. Foster^a ; Antonio C. Westphalen^c ; David R. Pettersson^a ; Megan L. Troxell^b ; Jeffry P. Simko^d ; Fergus V. Coakley^a ; ^{coakleyf@ohsu.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：MR imaging ; Prostate cancer ; Pseudocapsule ; Pathology
• 刊名：Clinical Imaging
• 出版年：2016
• 出版时间：May-June 2016
• 年：2016
• 卷：40
• 期：3
• 页码：365-369
• 全文大小：859 K

文摘

Clinicopathological correlates of prostate cancer associated with a pseudocapsule at T2-weighted magnetic resonance (MR) imaging are presented in a retrospective series of 15 patients. Of 15 tumors, 14 involved the peripheral zone. Extracapsular extension was seen in 14 cases. Tumor Gleason score was 8 or above in 12 of 15 cases, and ductal type adenocarcinoma was identified in 4 cases. Step section histopathological correlation (n = 5) demonstrated that the pseudocapsule corresponded with dense compressive or reactive peritumoral fibrosis. A pseudocapsule around prostate cancer at T2-weighted MR imaging is a rare finding that appears to be associated with high grade and stage disease.