New breath for rotavirus vaccines

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• 作者：Umesh D. Parashar ; ^{uparashar@cdc.gov} ; Joseph S. Bresee ; Marc-Alain Widdowson ; Jon R. Gentsch
• 刊名：Drug Discovery Today: Therapeutic Strategies
• 出版年：2006
• 出版时间：Summer 2006
• 年：2006
• 卷：3
• 期：2
• 页码：159-165
• 全文大小：325 K

文摘

New vaccines against rotavirus, the leading cause of severe childhood gastroenteritis worldwide, are on the threshold of introduction into immunization programs in affluent nations. A reduction of the health burden and costs of severe rotavirus disease in these countries should be evident within 2? years of vaccine introduction. However, realizing the full potential of these vaccines will require demonstration of their efficacy and ensuring their affordability in the poorest populations where rotavirus kills >500,000 children annually.