A study on the cytotoxicity of carbon-based materials
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- 作者：Dipendu Sahaa ; dsaha@mail.widener.edu" class="auth_mail" title="E-mail the corresponding author ; Caryn L. Heldtb ; Maria F. Gencoglub ; K. Saagar Vijayaragavanb ; Jihua Chenc ; Ashish Saksuleb
- 关键词：Carbon materials ; Cytotoxicity ; Reactive oxygen species (ROS) ; ATP depletion
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：68
- 期：Complete
- 页码：101-108
- 全文大小：1914 K
文摘
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Carbon materials demonstrated size dependent cytotoxicity in Caco-3 cells.
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None of the carbons materials demonstrated reactive oxygen species generation (ROS).
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Carbon materials demonstrated lowering of metabolic activity by ATP depletion.
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This study revealed that the size is the key factor of carbon-based toxicity.