The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis

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• 作者：Carmen Gerlach¹ ; ⁵ ; E. Ashley Moseman¹ ; ⁴ ; ⁵ ; Scott M. Loughhead¹ ; ⁵ ; David Alvarez¹ ; Anthonie J. Zwijnenburg¹ ; Lisette Waanders¹ ; Rohit Garg¹ ; Juan C. de la Torre² ; Ulrich H. von Andrian¹ ; ³ ; ⁶ ; ^{uva@hms.harvard.edu}
• 刊名：Immunity
• 出版年：2016
• 出版时间：20 December 2016
• 年：2016
• 卷：45
• 期：6
• 页码：1270-1284
• 全文大小：3538 K
• 卷排序：45

文摘

CX3CR1 correlates with the degree of effector CD8+ T cell differentiation CX3CR1 delineates three Tmem populations with distinct homeostatic properties Effector memory T cells are largely excluded from peripheral tissues CX3CR1int cells are the predominant Tmem subset surveying peripheral tissues