Antioxidant intervention attenuates oxidative stress in children and teenagers with Down syndrome
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- 作者：Eduardo Benedetti Parisottoa ; Thais Regina Garleta ; Vera Lú ; cia de Liz Oliveira Cavallib ; Ariane Zamonerb ; Julia Salvan da Rosac ; Juliana Bastosd ; Gustavo Amadeu Micked ; Tania Silvia Frö ; dec ; Rozangela Curi Pedrosab ; Danilo Wilhelm Filhoa ; dawifi@ccb.ufsc.br" class="auth_mail
- 关键词：Down syndrome ; Reactive oxygen species ; Oxidative stress ; Antioxidant therapy
- 刊名：Research in Developmental Disabilities
- 出版年：June 2014
- 年：2014
- 卷：35
- 期：6
- 页码：1228-1236
- 全文大小：863 K
文摘
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Down syndrome is associated with systemic oxidative stress.
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Antioxidant intervention attenuates oxidative stress in children with Down syndrome.
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Antioxidant supplementation attenuates the oxidative damage in Down syndrome patients.
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Vitamins E and C therapy improves antioxidant status in Down syndrome children's blood.
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Vitamin supplementation restored glutathione depletion in Down syndrome children.