A medical elaboration on von Willebrand disease with its dental management

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• 作者：M. Aparna¹ ; ^{appu.rags@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：von Willebrand disease ; Bleeding disorder ; Dental management
• 刊名：Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：28
• 期：5
• 页码：442-445
• 全文大小：399 K

文摘

von Willebrand disease (vWD) is the most common type of autosomally inherited bleeding disorder representing a range of quantitative and qualitative pathologies of the adhesive glycoprotein, von Willebrand factor (vWF). Since symptoms are often mild, a significant majority of patients remain undiagnosed.

Method

A review from the literature which imparts the knowledge on background, pathophysiology, classification, diagnostic measures and treatment modalities of this fatal bleeding disorder.

Results

With all forms of vWD, however, bleeding episodes can be severe and may require treatment.

Conclusions

A primary care physician should play a role in recognizing the signs and symptoms of vWD and in referring patients for proper management. The treatment of bleeding in vWD involves the use of desmopressin and plasma-derived vWF concentrates and a variety of adjunctive agents.