Intrathymic T-cell migration: a combinatorial interplay of extracellular matrix and chemokines?
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- 作者：Savino ; Wilson ; Mendes-da-Cruz ; Daniella A. ; Silva ; Joã ; o S. ; Dardenne ; Mireille ; Cotta-de-Almeida ; Viní ; cius
- 关键词：chemokines ; cell migration ; T-cell proliferation ; Molecular Medicine ; Immunology ; Cell biology
- 刊名：Trends in Immunology
- 出版年：2002
- 出版时间：June 1, 2002
- 年：2002
- 卷：23
- 期：6
- 页码：305-313
- 全文大小：375 K
文摘
Cell migration is crucial for intrathymic T-cell differentiation. Chemokines and extracellular matrix proteins per se induce thymocyte migration, and recent data suggest a combinatorial role for these molecules in this event.