Impairment on a self-ordered working memory task in patients with early-acquired hippocampal atrophy
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- 作者：Sharon Gevaa ; s.geva@ucl.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Janine M. Coopera ; 1 ; janine.cooper@mcri.edu.au" class="auth_mail" title="E-mail the corresponding author ; David G. Gadianb ; d.gadian@ucl.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Mortimer Mishkina ; c ; mishkinm@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author ; Faraneh Vargha-Khadema ; f.vargha-khadem@ucl.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 关键词：aMCI ; amnesic mild cognitive impairment ; CMS ; children memory scale ; DLPFC ; dorsolateral prefrontal cortex ; ECMO ; extracorporeal membrane oxygenation ; FSIQ ; full scale IQ ; IFG ; inferior frontal gyrus ; RT ; response time ; SOPT ; self-ordered pointing task ; TGA ; transposition of the great arteries ; VLPFC ; ventrolateral prefrontal cortex ; WAIS ; Wechsler adult intelligence scale ; WISC-IV ; Wechsler intelligence scale for children IV ; WMS ; Wechsler memory scale
- 刊名：Developmental Cognitive Neuroscience
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：20
- 期：Complete
- 页码：12-22
- 全文大小：1546 K
文摘
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Patients with early onset hippocampal damage were impaired on a working memory task.
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Impairment was evident only on those trials when memory load was intermediate.
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Hippocampal volume correlated with behaviour when memory load was intermediate/high.
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Patients showed no proactive interference.
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Patients showed no effect of age at injury on performance.