Event-related potentials reflect the efficacy of pharmaceutical treatments in children and adolescents with attention deficit/hyperactivity disorder
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- 作者：Kazuhiko Yamamuroa ; Toyosaku Otaa ; toyosaku@naramed-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Junzo Iidab ; Yoko Nakanishia ; Hiroki Matsuurac ; Mitsuhiro Uratanid ; Kosuke Okazakia ; Naoko Kishimotoa ; Shohei Tanakaa ; Toshifumi Kishimotoa
- 关键词：ADHD ; attention deficit/hyperactivity disorder ; MPH ; methylphenidate ; ATX ; atomoxetine ; DA ; dopamine ; NE ; norepinephrine ; ERPs ; event-related potentials ; OCD ; obsessive-compulsive disorder ; MMN ; mismatch negativity ; SCIS-NP ; Structured Clinical Interview for DSM-IV Axis Disorders Non-Patient Edition ; K-SADS-PL ; Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version ; WISC-IV ; Wechsler Intelligence Scale for Children ; Fourth Edition ; FIQ ; ful
- 刊名：Psychiatry Research
- 出版年：2016
- 出版时间：30 August 2016
- 年：2016
- 卷：242
- 期：Complete
- 页码：288-294
- 全文大小：514 K
文摘
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P300 and MMN characteristics differed between ADHD and control participants.
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Two months of ATX treatment significantly reduced P300 latencies towards normal.
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Two months of ATX treatment significantly increased MMN amplitude towards normal.
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ERPs could be useful tools for evaluating the pharmacological effects of ATX.
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Differences in ERPs might reflect different mechanisms of action for MPH and ATX.