Aphrodisiac activity of Phlegmariurus saururus in copulating and noncopulating male rats

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• 作者：Marcela Birri^a ; Mariana Vallejo^a ; Miguel Carro-Juá ; rez^b ; A. Mariel Agnese^a ; ^{magenese@fcq.unc.edu.ar}
• 关键词：Phlegmariurus saururus decoction ; Sexual behavior ; Pro-sexual activity ; Sexually expert rats ; Sexually inactive rats ; Ejaculation latency
• 刊名：Phytomedicine
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：24
• 期：Complete
• 页码：104-110
• 全文大小：567 K
• 卷排序：24

文摘

Phlegmariurus saururus is popularly known in Argentina as aphrodisiac. For this reason, it was previously investigated and determined that the decoction of this plant elicits pro-ejaculatory activity and increases the ejaculatory potency in the Fictive Ejaculation Model.Hypothesis/Purposethe decoction of P. saururus facilitates sexual behavior in sexually experienced male rat and induces copulatory behavior in non-copulating male rats.MethodsThe extraction method (decoction) was validated through Selectivity, Accuracy and Precision, by identification of the majority alkaloids, expressed as sauroxine. Male (sexually experienced and noncopulating) and female (receptive) Wistar rats were used to determine sexual behavior. Sildenafil was used as positive control. The following variables were evaluated: Mount Latency, Intromission Latency, Ejaculation Latency, Post Ejaculatory Interval, as well as the Mounts and Intromissions Number.ResultsIn sexually experienced male rats, P. saururus decoction stimulates sexual arousal and facilitates sexual execution. In noncopulating male rats, this decoction induces copulation with behavioral characteristics similar to sexually experienced animals.ConclusionP. saururus possesses aphrodisiac activity in copulating and noncopulating male rats.